HumanitiesWeb.org - Glossary definition: Italian War of 1542
Italian War of 1542

The Italian War of 1542 (1542–45) occurred when Francis I of France, allying himself with Suleiman I of the Ottoman Empire, launched a final invasion of Italy. A Franco-Ottoman fleet captured the city of Nice in August 1543, and laid siege to the citadel. The defenders were relieved within a month. The French, under François, Count d'Enghien, defeated an Imperial army at the Battle of Ceresole in 1544, but the French failed to penetrate further into Lombardy. Charles V, Holy Roman Emperor, and Henry VIII of England then proceeded to invade northern France, seizing Boulogne and Soissons. A lack of cooperation between the Spanish and English armies, coupled with increasingly aggressive Ottoman attacks, led Charles to abandon these conquests, restoring the status quo once again.


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