| Timeline |
| 1452 |
Born 15 April at Anchian near Vinci, Tuscany |
| 1469 |
Begins apprenticeship at the workshop of Verrocchio in Florence |
| 1472 |
Admitted to the Company of Painters |
| 1478 |
Becomes an independent master |
| 1482 |
Moves to Milan to enter the service of Ludovico 'the Moor' Sforza |
| 1492 |
Visits Rome |
| 1496 |
Meets mathematician Luca Pacioli, with whom he studies Euclid |
| 1499 |
Flees from Milan when the French invade Italy |
| 1500 |
Travels in Venice and Florence |
| 1502 |
Employed as military engineer to Cesare Borgia
|
| 1506 |
Invited to Milan by French King Louis XII |
| 1507 |
In Florence again |
| 1507 |
Named court painter to King Louis XII of France |
| 1508 |
Returns to Milan |
| 1513 |
Works for Giuliano de' Medici in Rome |
| 1514 |
In Rome under the patronage of the new pope, Leo X - living in the Palazzo Belvedere |
| 1516 |
Moves to France, to work for Francois I |
| 1519 |
Dies 2 May at the Castle of Cloux near Amboise, France |